Analysis of spontaneous reporting of suspected adverse drug reactions for non-analgesic over-the-counter drugs from 2008 to 2017.
By: Bukic J, Rusic D, Mas P, Karabatic D, Bozic J et al.
BMC Pharmacol Toxicol. 2019 Oct 18;20(1):60.
Summary: Adverse drug reaction (ADR) reporting practices by health care professionals remain poor. While OTC drugs are perceived as safe, they can also cause ADRs. The objective of this study was to analyze ADR reporting for OTC drugs in a 10-year period in Croatia. There were 547 ADRs of OTC drugs reported in total. Pharmacists reported 45.4% of all ADRs, and were the most frequent reporters. The majority of reports (49.2%) were obtained from consumers. ADRs were most frequently observed in patients aged 70 years and older (15% of ADRs). Five percent of all reports were accidental exposures among children.