by D C Bradford, D L McCammon, B C Page, C A Richardson, K A Hunter
Bradford D C.et al. Principles of Actual Use Trials. SelfCare 2010;1(4):117-123
The actual use trial is a method for assessing safety of a prescription drug under conditions resembling non-prescription use. Thus, it is generally a key study in an application for the over-the-counter (OTC) switch of a drug in the U.S.